SYMPTOMS

Symptoms of Fluoroquinolone Toxicity include

Musculoskeletal

•   Joint pain (arthralgia), stiffness, swelling

•   Joint popping or cracking

•   Tendon pain, tendonitis, tendonosis, tendon rupture

•   Muscle wasting, atrophy, pain, weakness

•   Muscle cramps, spasms, twitching

•   Limb pain and swelling

Neuropsychiatric

•   Lightheadedness, loss of balance, dizziness, vertigo

•   Panic attacks

•   Brain fog, memory loss, impaired concentration, confusion, disorientation

•   Hallucinations, delirium

•   Feeling like something crawling on/under skin

•   Malaise, fatigue

•   Insomnia

•   Palpitations

•   Headaches

•   Nightmares

•   Seizures

•   Anxiety/Depression

•   Psychosis, Paranoia, phobias

•   Suicidal thoughts, feelings of detachment

•   Restlessness, nervousness, agitation

 Peripheral Nervous System

•   Peripheral neuropathy

•   Numbness, Tingling

•   Burning pain

•   Electrical or shooting pain

•   Twitching, tremors

•   Pins & needles sensation

•   Paresthesias

•   Prickling

•   Nerve damage

Senses Events

•   Eye pain Diminished, blurred, double vision

•   Floaters

•   Photosensitivity, photo toxicity

•   Sensitivity to light (photophobia)

•   Retina tear or detachment

•   Ear pain, pressure in ears

•   Tinnitus

•   Hearing impairment

•   Loss or altered taste

•   Loss of smell



Cardiovascular

•   Palpitations

•   Tachycardia

•   Chest pain/discomfort

•   Aortic Aneurysm and Dissection

•   Prolongation of the QT Interval

Skin

•   Ongoing skin rash or acne

•   Sweating

•   Photosensitivity

•   Skin sensitivity to touch

•   Hair loss

•   Flushing

Other

•   Mast Cell Activation Syndrome (MCAS) through MRGPRX2

•   Hypersensitivities, anaphylaxis

•   Dysbiosis

•   Blood glucose disturbances

•   Exacerbation of Myasthenia Gravis

•   Organ Failure

•   Death